Mother of Colorado shooting-spree suspect says son was a compassionate kid

The evidence appears to be mounting that a Colorado prison parolee, killed in a shootout this week in Texas, may have been involved in the brazen murder of the head of Colorado's prison system. NBC's Kristen Dahlgren reports.

By Erin McClam, Staff Writer, NBC News

The mother of the man suspected of gunning down the top prisons official in Colorado says her son was a compassionate child who ?drifted into a dark period? after the death of his 16-year-old sister.

Jody Mangue wrote that her son, Evan Ebel, adored animals and walked up to the mentally ill in restaurants to engage them in conversation.

?He was full of energy, was funny and lit up a room,? she wrote in a posting on a website dedicated to the memory of the sister, Marin Ebel, who was killed in a car crash in January 2004.

Ebel, 28, is a suspect in the shooting death of Tom Clements, the head of the Colorado Department of Corrections, who was killed last Tuesday when he opened the front door of his home.

Ebel was killed Thursday after a wild chase and gunfight with sheriff?s deputies in Texas. He is also suspected in the killing of a Domino?s pizza delivery man outside Denver on March 17.

Mangue wrote that her son was already struggling before his sister?s death, but that the loss ?threw him over the edge.?

?His life deteriorated after that and he just became numb and lost his direction altogether,? she wrote. In the posting, she thanked friends and strangers who have offered her support since last week.

The Denver Post reported over the weekend that Ebel?s documented decline began in October 2003, when he pointed a gun at the head of an acquaintance and demanded cash.

In the spring of 2004, police told the newspaper, Ebel carjacked a stranger, pointed a gun at a woman and accidentally shot himself in two separate incidents, once in the stomach and once in the leg.

He was sentenced to eight years in prison after pleading guilty in the carjacking case and was paroled in January of this year.

Colorado Department of Corrections / Reuters

Evan Spencer Ebel in an undated Colorado booking photo.

Colorado Gov. John Hickenlooper, a friend of Ebel?s father, told CNN on Sunday that the suspect always ?just seemed to have this bad streak, a streak of cruelty and anger.?

Law enforcement officials have said Ebel was involved with a white supremacist prison gang, the 211 Crew, which outside groups say demands that some of its members commit crimes once they leave prison.

Mangue wrote that her son was his own person, not a follower.

Despite having been linked to white supremacists, she wrote, ?most white people in prison are automatically put in that category and sometimes forced to say they are even when they are not.?

Reuters contributed to this report.

Related:

Suspect in Colorado killing had a ?bad, bad streak?

Colorado governor knew family of man eyed in prison chief slaying

This story was originally published on Mon Mar 25, 2013 11:48 AM EDT

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Making an IT Department Sustainable in 2013 - Environmental Leader

In modern day society, there is nothing more positive than going green while simultaneously saving money.? The Earth we live within and the economy we work within are both in conditions that require progression from the human race. This applies across the board from personal homes to large corporations. A specific area I?d like to focus is Information Technology. IT departments across the United States maintain business processes and information, but they also use a substantial amount of energy. Using more energy often requires increased monetary resources, creating a substantial incentive.

Everyone agrees at least to a certain degree that progression towards sustainability is a good idea. Taking action within the IT industry can be very influential in the movement because technology services are both widespread and necessary across the country. Below I have offered ways that IT leadership can reorganize operative priorities with the goal of increased energy efficiency and financial savings.

1.???? Start a recycle program.

In 2013, the talk of having a recycle bin should be a past conversation. We?re going to focus on bigger issues here. To start, when there are any electronics that are phased out of the department, recycle them. It?s more complicated than a paper grocery bag, but it?s possible to find out how and where to recycle electronics on the EPA website.

This would be a massive step in the right direction. A country-wide movement of electronic recycling could change the whole landscape of reprocessing. There are seemingly infinite amounts of electronics, new and old, littered around office buildings and homes across America. A recycling program of this nature could really make a difference to the planet.

In addition to helping our environment, recycling can also help an IT department and company budget. A specific way to do this is to buy refurbished computers rather than brand new. Doing so for an office of 100 people will decrease demand on a major producer to build 100 new computers, and also save you money on a reduced purchase price. It?s all a numbers game, and it can be improved.

?2.???? Small office changes.

Any change is good when it comes to saving energy. Making actionable changes such as utilizing software that can automatically switch the power off of machines when they aren?t being used is a start. So many times a large printer will sit in idle with its power on overnight and throughout the weekend.

Another idea as a CIO leader or IT manager is to implement a rule that screen savers are not allowed, opting instead for an allowed time period of 20 minutes before the ?sleep? function kicks in on the computer. Even smaller, yet still actionable, a leader can implement dual sided printing and very strict office recycling with all possible materials used on a daily basis.

The little differences can make a big impact if all done simultaneously. It can help, and the most important factor is that it shouldn?t make the job any more difficult or inconvenient.

3.???? Donate.

Before this option can be executed, classified and important information obviously needs to be erased. With the type of training and people in an IT department, this shouldn?t be an issue. An IT leader can identify a month each year when the office focuses on donating unneeded electronics to the local Good Will or other store that accepts donations. This could also help the budget as contributions could be tax deductible.

The months leading up to the holidays could be a perfect time for IT leaders to consider. During this time frame, the donated electronics could serve as potential gifts for people in need.

?4.???? Consider a four day work week.

While this can be difficult in the IT industry, it is far from impossible. One idea to work around the issue of services being necessary more than four days is to rotate which employees have to work on Friday. This increases the department?s potential to go green by reducing the full energy output to four days. This can make a huge impact both budget-wise and environmental wise over a long period of time.

Four day work weeks also help prevent people from driving to and from the office so frequently. The opportunity is also there to offer a work from home situation for certain employees that have roles where it may be feasible.

Businesses across America, specifically the IT departments within those businesses, owe it to the world to make a move toward more sustainable practices. Not only can it help the environment through a widespread channel of exposure, it can also help from a financial standpoint. A major barrier to environmentally sound progress has been that it isn?t financially viable. While this is still true in some regard, it isn?t entirely when an IT department is concerned. A creative CIO or IT manager can make a difference, if they want to.

Grant Davis is a data modeler by day who writes by night. His passion for computers started when he discovered instant messaging in junior high school. When Grant isn?t trying to climb through the computer screen he writes for BMC, a leading job scheduling software provider.

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Source: http://www.environmentalleader.com/2013/03/13/making-an-it-department-sustainable-in-2013/

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Study shows key enzyme missing from aggressive form of breast cancer

Friday, March 1, 2013

A new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain ? providing insight into potential therapeutic targets to treat the aggressive cancer. Zhou's study is unique in that his lab is the only one in the country to specifically study the metabolic process of triple-negative breast cancer cells.

Normally, all cells ? including cancerous cells ? use glucose to initiate the process of making Adenosine-5'-triphosphate (ATP) for fuel to carry out essential functions. This process, called glycolysis, leads to other processes that use oxygen to make higher quantities of ATP ? but solid tumor cells, which have little access to oxygen, are forced to rely almost exclusively on aerobic glycolysis for survival.

Zhou's study, published in Cancer Cell, showed that the powerful transcription factor complex Snail-G9a-Dnmt1 is over-expressed in triple-negative breast cancer, inhibiting the enzyme 1,6-bisphosphate (FBP1). The loss of this enzyme shuts down the glucose anabolic pathway and promotes the glucose catabolic pathway, leading to a large amount of glucose entering the tumor cells and thus "feeding" the aggressive cancer. This metabolic switch empowers the triple-negative breast cancer cells to suck more glucose from the body, increasing macromolecule biosynthesis in tumor cells and maintaining ATP production despite a dearth of nutrients and an oxygen-free environment.

Triple-negative breast cancer is the most deadly subtype of breast cancer, and tends to occur in women at a younger age. This subtype of breast cancer has poor clinical outcomes due to the early metastasis of tumor cells, resistance to chemotherapy, and the lack of specific drugs that target it. Identifying this change in the cancer's metabolic process provides major insight into developing drugs to target the disease, Zhou says.

"These findings present significant insights regarding the development and progression of triple-negative breast cancer," said Zhou, associate professor of molecular and cellular biochemistry at UK. "They indicate that targeting the metabolic alteration will lead to an effective approach for treating this deadly disease."

Zhou's research was aided by the team in the Free Radical Biology in Cancer Shared Resource Facility (FRBC) of the Markey Cancer Center, directed by Dr. Allan Butterfield. The FRBC used an instrument called the Seahorse XF-96 Flux Analyzer to test and confirm the predictions of Zhou's findings in triple-negative breast cancer.

"The significance of this study rests in proving that triple negative breast cancer cells utilize glycolysis for survival and growth," Butterfield said. "The FRBC will assist Dr. Zhou in furthering this exciting research, potentially helping to identify key proteins in triple negative breast cancer cells that are expressed or modified differently than in control cells. Such knowledge may lead to new insights to potential approaches to treat this aggressive cancer."

###

University of Kentucky: http://www.uky.edu

Thanks to University of Kentucky for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127084/Study_shows_key_enzyme_missing_from_aggressive_form_of_breast_cancer

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Irving ISD students to attend business ethics summit | Irving Blog

Frank Broyles

About 250 students from each of the Irving school district?s four high schools and eight middle schools will learn about business ethics today. They will attend a seminar put on by Dr. Paul Melendez from the University of Arizona?s Center for Leadership Ethics. The University of Dallas is hosting the event.

Funding for the program will come primarily from La Buena Vida Foundation, but the Irving ISD, the YMCA and some local businesses and business leaders also are contributing. Attorney Frank Boyles is chairman of the program and said he hopes to make this an annual event.

The program will start with Dr. Melendez presenting an ethical decision making model. Then three case studies will be presented with some interaction with the students: a Facebook case, a case based on the game Grand Theft Auto and an underwater mortgage case. Included in the third case will be a professional panel comprised of the following: Jacqueline R. Peterson , attorney, Office of the General Counsel, Hewlett-Packard Company (she currently serves as its Global Anti-Corruption Attorney and Director, Ethics & Compliance, Americas); Areya Holder, attorney and Department of Justice Chapter 7 panel trustee for the northern district of Texas (she also has a private bankruptcy practice); and C. D. Heinen, senior vice president at Texas Security Bank (he?s been in the banking business in the Dallas area since 1974).

For more details about the program, visit http://ethics.eller.arizona.edu/outreach.

This entry was posted in Charity, Irving, Irving ISD, University of Dallas and tagged Frank Broyles, Irving ISD, La Buena Vida Foundation, University of Dallas by Deborah Fleck / News Assistant. Bookmark the permalink.

Source: http://irvingblog.dallasnews.com/2013/03/irving-isd-students-to-attend-business-ethics-summit.html/

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HTC confirms some current phones will receive Sense 5 update

MADRID, Feb 27 (Reuters) - Lionel Messi has rarely been accused of failing to deliver in big games, having scored in two European Cup finals, but after subdued performances against AC Milan and Real Madrid, questions are being asked. The four-times World Player of the Year and leading scorer in one of the greatest club teams of all time, was a shadow of his usual self at the San Siro in a Champions League last-16 first leg last week, when Barcelona slumped to a 2-0 defeat. ...

Source: http://news.yahoo.com/htc-confirms-current-phones-receive-sense-5-031002025.html

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Obama chides GOP for killing plan to address cuts

WASHINGTON (AP) ? President Barack Obama is chiding Senate Republicans for blocking a Democratic plan to replace automatic spending cuts that are set to kick in Friday.

Senate Republicans objected to $55 billion worth of new taxes in the Democratic plan. It would have replaced the cuts with tax increases on millionaires and spending reductions over 10 years.

Obama says Republicans chose to cut services for kids, older people and the military rather than close loopholes for the rich. He says Republicans want the middle class alone to pay for deficit reduction.

Republicans floated their own plan to give Obama more flexibility to find $85 billion in spending cuts this year. Democrats and tea party Republicans killed that plan Thursday.

Obama and congressional leaders are to meet Friday to discuss potential ways ahead.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-02-28-US-Budget-Battle-Obama/id-a9851a6ac68945dfb4d9e5bbc0df643d

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Colorado task force ponders how to tax legal pot

DENVER (AP) ? Pot smokers in Colorado were the biggest winners in the vote that legalized the drug. Now state regulators are working out the details of exactly how to tax it, so the benefits are shared statewide in the form of increased revenue.

A state panel meets Thursday to draft final recommendations based on the voter-approved marijuana legalization question that asked for excise taxes up to 15 percent to fund school construction.

Colorado lawmakers could set a lower tax, or they could add sales taxes beyond the current statewide 2.9 percent. Legislators could even create a special new "marijuana tax" for consumers, plus a series of required licensing fees for growers and sellers. Besides schools, the taxes must fund marijuana safety enforcement and drug education measures.

Any option would have to go back to voters for final approval.

Marijuana proponents and critics agree that taxes should be hefty. But if levies are too high, legal pot could be so expensive that people continue buying it underground.

"If this doesn't work and taxes are so high the black market still dominates, then what was the point?" asked Mike Elliott of Colorado's Medical Marijuana Industry Group.

Fiscal analysts have no idea where to begin predicting how much tax pot smokers could produce. The unknowns include how many people are buying pot now and what they're paying, how many people will start smoking marijuana now that it's legal and whether prices will drop once commercial sales begin. If the federal government blocks commercial pot sales, the marijuana tax windfall would be zero.

"It's a big question mark," said Colorado state budget analyst Dan Krug, who ran through multiple tax scenarios with the marijuana task force set up to recommend legislation to regulate weed. Krug's estimates ranged from a few million dollars a year up to $72 million annually, depending on tax rates and growth of the industry.

In Washington, the only other state to legalize marijuana for recreational use, the tax picture is clearer.

Voters there set 25 percent taxes at each of three different stages ? from growers to processors to consumers. The measure also defined exact spending levels on things like education. For example, Washington will spend exactly $20,000 on Web-based education on the health and safety risks of marijuana.

Colorado's task force is likely to adopt a vague recommendation asking state lawmakers to set excise fees and add licensing fees steep enough to cover the costs of regulation. They'll leave it lawmakers to figure out those exact costs.

Task force members will also settle recommendations Thursday on regulations unrelated to taxes, including rules for growing marijuana at home.

The task force already has asked for potency labels, limited marijuana advertising, set residency requirements for marijuana workers and limited commercial sales to less than an ounce. The group decided against a residency requirement for pot customers, opening the door for marijuana tourism.

___

Kristen Wyatt is on Twitter at http://www.twitter.com/APkristenwyatt

Source: http://news.yahoo.com/colorado-task-force-ponders-tax-legal-pot-162809695.html

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